Preliminary Pharmacogenomic-Based Predictive Models of Tamoxifen Response in Hormone-dependent Chilean Breast Cancer Patients

• Main Authors: Carla Miranda (Author), Macarena Galleguillos (Author), Roberto Torres (Author), Karla Tardón (Author), Dante D. Cáceres (Author), Kuen Lee (Author), María A. Redal (Author), Nelson M. Varela (Author), Luis A. Quiñones (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tamoxifen (TAM), a selective oestrogen receptor modulator, is one of the most used treatments in oestrogen receptor-positive (ER+) early and metastatic breast cancer (BC) patients. The response to TAM has a high degree of inter-individual variability. This is mainly due to genetic variants in CYP2D6...