Testing the Translational Power of the Zebrafish: An Interspecies Analysis of Responses to Cardiovascular Drugs

• Main Authors: Luigi Margiotta-Casaluci (Author), Stewart F. Owen (Author), Mariann Rand-Weaver (Author), Matthew J. Winter (Author)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The zebrafish is rapidly emerging as a promising alternative in vivo model for the detection of drug-induced cardiovascular effects. Despite its increasing popularity, the ability of this model to inform the drug development process is often limited by the uncertainties around the quantitative relev...