Generalized ROC methods for immunogenicity data analysis of vaccine phase I studies in a seropositive population
Immunogenicity data from phase 1 vaccine studies can be difficult to interpret, especially in seropositive populations and when multiple assays are used. We developed 3 statistical methods (Youden index [YI] threshold, receiver-operating characteristic relative to baseline [ROC-B], and ROC of postdo...
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Main Authors: | , , , , |
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Format: | Book |
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Taylor & Francis Group,
2018-11-01T00:00:00Z.
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Internet
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A1234.567 |
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Copy 1 | Available |