New mutations in the <it>PKD1 </it>gene in Czech population with autosomal dominant polycystic kidney disease

• Main Authors: Merta Miroslav (Author), Lnenicka Petr (Author), Kebrdlova Vera (Author), Svobodova Stanislava (Author), Reiterova Jana (Author), Stekrova Jitka (Author), Viklicky Ondrej (Author), Kohoutova Milada (Author)
• Format: Book
• Published: BMC, 2009-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary renal disease. The disease is caused by mutations of the <it>PKD1 </it>(affecting roughly 85% of ADPKD patients) and <it>PKD2 </i...