Erythrodiol, an Olive Oil Constituent, Increases the Half-Life of ABCA1 and Enhances Cholesterol Efflux from THP-1-Derived Macrophages

• Main Authors: Limei Wang (Author), Sarah Wesemann (Author), Liselotte Krenn (Author), Angela Ladurner (Author), Elke H. Heiss (Author), Verena M. Dirsch (Author), Atanas G. Atanasov (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cholesterol efflux (ChE) from macrophages is an initial step of reverse cholesterol transport (RCT). The ATP-binding cassette transporter A1 (ABCA1) is a key transporter for ChE and its increased expression is regarded to attenuate atherosclerosis. Thus, the identification and characterization of mo...