Suppression of the Insulin Receptors in Adult Schistosoma japonicum Impacts on Parasite Growth and Development: Further Evidence of Vaccine Potential.

• Main Authors: Hong You (Author), Geoffrey N Gobert (Author), Pengfei Cai (Author), Rong Mou (Author), Sujeevi Nawaratna (Author), Guofu Fang (Author), Francois Villinger (Author), Donald P McManus (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To further investigate the importance of insulin signaling in the growth, development, sexual maturation and egg production of adult schistosomes, we have focused attention on the insulin receptors (SjIRs) of Schistosoma japonicum, which we have previously cloned and partially characterised. We now...