Gene expression profiling of fibroblasts in a family with LMNA-related cardiomyopathy reveals molecular pathways implicated in disease pathogenesis

Abstract Background Intermediate filament proteins that construct the nuclear lamina of a cell include the Lamin A/C proteins encoded by the LMNA gene, and are implicated in fundamental processes such as nuclear structure, gene expression, and signal transduction. LMNA mutations predominantly affect...

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Main Authors: Halida P. Widyastuti (Author), Trina M. Norden-Krichmar (Author), Anna Grosberg (Author), Michael V. Zaragoza (Author)
Format: Book
Published: BMC, 2020-07-01T00:00:00Z.
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