Geranylgeranylacetone Ameliorates Skin Inflammation by Regulating and Inducing Thioredoxin via the Thioredoxin Redox System

• Үндсэн зохиолчид: Tiancheng Jin (Зохиогч), Yitong You (Зохиогч), Wenjie Fan (Зохиогч), Junyang Wang (Зохиогч), Yuhao Chen (Зохиогч), Shujing Li (Зохиогч), Siyuan Hong (Зохиогч), Yaxuan Wang (Зохиогч), Ruijie Cao (Зохиогч), Junji Yodoi (Зохиогч), Hai Tian (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-08-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Geranylgeranylacetone (GGA) exerts cytoprotective activity against various toxic stressors via the thioredoxin (TRX) redox system; however, its effect on skin inflammation and molecular mechanism on inducing the TRX of GGA is still unknown. We investigated the effects of GGA in a murine irritant con...