An Open Label Non-inferiority Trial Assessing Vibriocidal Response of a Killed Bivalent Oral Cholera Vaccine Regimen following a Five Year Interval in Kolkata, India.

• Main Authors: Suman Kanungo (Author), Sachin N Desai (Author), Jayanta Saha (Author), Ranjan Kumar Nandy (Author), Anuradha Sinha (Author), Deok Ryun Kim (Author), Barnali Bannerjee (Author), Byomkesh Manna (Author), Jae Seung Yang (Author), Mohammad Ali (Author), Dipika Sur (Author), Thomas F Wierzba (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The bivalent killed oral cholera vaccine (OCV) provides 65% cumulative protection over five years. It remains unknown whether a boosting regimen can maintain protection in previously immunized populations. This study examines the immunogenicity and safety of an OCV regimen given five year...