Multisite gynecologic endometrioid adenocarcinomas: Can mutation profiling be used to distinguish synchronous primary cancers from metastases?

• Main Authors: Dominique Barnes (Author), Nissreen Mohammad (Author), Lien Hoang (Author), Michael Anglesio (Author), Robert L. Hollis (Author), Charlie Gourley (Author), Heather C. Stuart (Author), Mark S. Carey (Author), Gavin C.E. Stuart (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It is well recognized that some patients with endometrioid gynecological cancers have tumors arising in multiple sites (ovary, endometrium, and endometriosis) at the time of diagnosis. Molecular analysis has helped discern whether these multisite cancers represent synchronous primary tumors or alter...