SGC-CK2-1 Is an Efficient Inducer of Insulin Production and Secretion in Pancreatic β-Cells

• Những tác giả chính: Mandy Pack (Tác giả), Claudia Götz (Tác giả), Selina Wrublewsky (Tác giả), Mathias Montenarh (Tác giả)
• Định dạng: Sách
• Được phát hành: MDPI AG, 2021-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

The pyrazolopyrimidine based compound SGC-CK2-1 is a potent and highly specific CK2 inhibitor and a new tool to study the biological functions of protein kinase CK2 irrespective from off-target effects. We used this compound in comparison with the well-established CK2 inhibitor CX-4945 to analyze th...