Identification of PROK2 gene polymorphisms as predictors of methamphetamine use disorder risk and indicators of craving scale in the Chinese Han population

• Main Authors: Zhao Jiang (Author), Tianxiao Zhang (Author), Wei Han (Author), Jing Xiao (Author), Wenpei Zhang (Author), Xiaochen Wang (Author), Jianing Liu (Author), Ying Yang (Author), Congying Yang (Author), Fanglin Guan (Author), Tao Li (Author), John P. Rice (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Methamphetamine use disorder (MUD) has become a global problem due to the highly addictive nature of methamphetamine. Earlier research have demonstrated that PROK2 functions as a compensatory and protective response against neurotoxic stress by stimulating astrocyte reactivity. The aim o...