A Proposed Quantitative Index for Assessing the Potential Contribution of Reprogramming to Cancer Stem Cell Kinetics

• Główni autorzy: Xuefeng Gao (Autor), J. Tyson McDonald (Autor), Mamta Naidu (Autor), Philip Hahnfeldt (Autor), Lynn Hlatky (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2014-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Enrichment of cancer stem cells (CSCs) is thought to be responsible for glioblastoma multiforme (GBM) recurrence after radiation therapy. Simulation results from our agent-based cellular automata model reveal that the enrichment of CSCs may result either from an increased symmetric self-renewal divi...