Prevalence and genetic basis of Mycobacterium tuberculosis resistance to pretomanid in China

• Main Authors: Bing Zhao (Author), Huiwen Zheng (Author), Juliano Timm (Author), Zexuan Song (Author), Shaojun Pei (Author), Ruida Xing (Author), Yajie Guo (Author), Ling Ma (Author), Feina Li (Author), Qing Li (Author), Yan Li (Author), Lin Huang (Author), Chong Teng (Author), Ni Wang (Author), Aastha Gupta (Author), Sandeep Juneja (Author), Fei Huang (Author), Yanlin Zhao (Author), Xichao Ou (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pretomanid is a key component of new regimens for the treatment of drug-resistant tuberculosis (TB) which are being rolled out globally. However, there is limited information on the prevalence of pre-existing resistance to the drug. Methods To investigate pretomanid resistance ra...