Application of Cerebrospinal Fluid Host Protein Biosignatures in the Diagnosis of Tuberculous Meningitis in Children from a High Burden Setting

• Main Authors: Charles M. Manyelo (Author), Regan S. Solomons (Author), Candice I. Snyders (Author), Portia M. Manngo (Author), Hygon Mutavhatsindi (Author), Belinda Kriel (Author), Kim Stanley (Author), Gerhard Walzl (Author), Novel N. Chegou (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The diagnosis of tuberculous meningitis (TBM) especially in children is challenging. New tests are urgently needed for the diagnosis of the disease, especially in resource-limited settings. Methods. We collected cerebrospinal fluid (CSF) samples from children presenting with symptoms req...