Design, synthesis and determination of physical and chemical characteristics of glycoconjugates as model for oligosaccharide vaccines against vibrio cholerae

• Main Authors: Aleksandra Grozdanova (Author), Ana Poceva (Author), Katerina Milenkova (Author), Ljubica Suturkova (Author)
• Format: Book
• Published: University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical Association, 2003-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cholera is toxin-mediated enteroinfection, with epidemic character and there are approximately 120000 death cases per year worldwide. Protection against cholera has not been accomplished due to deficiencies in the licensed vaccines. Serum vibriocidal activity mediated by LPS antibodies is the only i...