Cardiac Ca2+ Channel-Blocking Effects of the Cyproheptadine Derivative AH-1058 in Isolated Guinea Pig Cardiomyocytes

• मुख्य लेखकों: Hideki Dohmoto (लेखक), Akira Takahara (लेखक), Hisayuki Uneyama (लेखक), Ryota Yoshimoto (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2003-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The Ca2+ channel-blocking efficacy of the cyproheptadine derivative AH-1058 (4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-[(E)-3-(3-methoxy-2-nitro)phenyl-2-propenyl]piperidine hydrochloride) was quantitatively assessed using isolated guinea pig cardiomyocytes. AH-1058 (0.001 ≫ 10 μM) and its mother c...