Atorvastatin mitigates cyclophosphamide-induced hepatotoxicity via suppression of oxidative stress and apoptosis in rat model

• मुख्य लेखकों: Maedeh Hamzeh (लेखक), Seyed Jalal Hosseinimehr (लेखक), Ali Reza Khalatbary (लेखक), Hamid Reza Mohammadi (लेखक), Ayat Dashti (लेखक), Fereshteh Talebpour Amiri (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Cyclophosphamide (CP), as a chemotherapy drug, induces hepatotoxicity through causing oxidative stress. Atorvastatin (ATV) at a low dose has antioxidant and anti-inflammatory properties. The present study was designed to investigate the protective effects of ATV against CP-induced hepatotoxicity in...