Novel Deep Sea Isoindole Alkaloid FGFC1 Exhibits Its Fibrinolytic Effects by Inhibiting Thrombin-Activatable Fibrinolysis Inhibitor

• Κύριοι συγγραφείς: Haixing Zhang (Συγγραφέας), Xiaozhen Diao (Συγγραφέας), Tingting Jiang (Συγγραφέας), Mingjun Wei (Συγγραφέας), Yue Su (Συγγραφέας), Jingjing Shen (Συγγραφέας), Chunlin Bao (Συγγραφέας), Wenhui Wu (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2024-10-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background: The thrombin-activatable fibrinolysis inhibitor (TAFI) is an important regulator in the balance between blood clot formation (coagulation) and dissolution (fibrinolysis), which is mainly activated by thrombin bonded with thrombomodulin (TM). Methods: In this study, the investigation focu...