Pharmacogenetics of pediatric acute lymphoblastic leukemia in Uruguay: adverse events related to induction phase drugs

• Main Authors: Gabriela Burgueño-Rodríguez (Author), Yessika Méndez (Author), Natalia Olano (Author), Magdalena Schelotto (Author), Luis Castillo (Author), Ana María Soler (Author), Julio da Luz (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In Uruguay, the pediatric acute lymphoblastic leukemia (ALL) cure rate is 82.2%, similar to those reported in developed countries. However, many patients suffer adverse effects that could be attributed, in part, to genetic variability. This study aims to identify genetic variants related to drugs ad...