A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals.

• Autores principales: Bobby Brooke Herrera (Autor), Donald J Hamel (Autor), Philip Oshun (Autor), Rolake Akinsola (Autor), Alani S Akanmu (Autor), Charlotte A Chang (Autor), Philomena Eromon (Autor), Onikepe Folarin (Autor), Kayode T Adeyemi (Autor), Christian T Happi (Autor), Yichen Lu (Autor), Folasade Ogunsola (Autor), Phyllis J Kanki (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Ebola virus (EBOV) caused more than 11,000 deaths during the 2013-2016 epidemic in West Africa without approved vaccines or immunotherapeutics. Despite its high lethality in some individuals, EBOV infection can produce little to no symptoms in others. A better understanding of the immune responses i...