A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals.

• Main Authors: Bobby Brooke Herrera (Author), Donald J Hamel (Author), Philip Oshun (Author), Rolake Akinsola (Author), Alani S Akanmu (Author), Charlotte A Chang (Author), Philomena Eromon (Author), Onikepe Folarin (Author), Kayode T Adeyemi (Author), Christian T Happi (Author), Yichen Lu (Author), Folasade Ogunsola (Author), Phyllis J Kanki (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ebola virus (EBOV) caused more than 11,000 deaths during the 2013-2016 epidemic in West Africa without approved vaccines or immunotherapeutics. Despite its high lethality in some individuals, EBOV infection can produce little to no symptoms in others. A better understanding of the immune responses i...