Transforming Growth Factor Beta Receptor 3 Haplotypes in Sickle Cell Disease Are Associated with Lipid Profile and Clinical Manifestations

• Main Authors: Rayra P. Santiago (Author), Camylla V. B. Figueiredo (Author), Luciana M. Fiuza (Author), Sètondji C. M. A. Yahouédéhou (Author), Rodrigo M. Oliveira (Author), Milena M. Aleluia (Author), Suellen P. Carvalho (Author), Cleverson A. Fonseca (Author), Valma M. L. Nascimento (Author), Larissa C. Rocha (Author), Caroline C. Guarda (Author), Marilda S. Gonçalves (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-β pathway is known to play a role in immune response, angiogenesis, inflammation, hematopoiesis, vascular inflammation, and cell proliferation. Polymorphisms in the transforming growth factor-beta...