Novel Antimicrobial Treatment Strategy Based on Drug Delivery Systems for Acute Otitis Media

• Main Authors: Masamitsu Kono (Author), Nafisa K. Umar (Author), Saori Takeda (Author), Makiko Ohtani (Author), Daichi Murakami (Author), Hideki Sakatani (Author), Fumie Kaneko (Author), Denisa Nanushaj (Author), Muneki Hotomi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite tremendous success of pneumococcal conjugated vaccine and antimicrobial treatment by amoxicillin, acute otitis media (AOM) still remains as a great medical concern. Failure of antimicrobial treatment includes several factors. The middle ear cavity is surrounded by bone tissue, which makes it...