Characterization of thrombin/factor Xa inhibitors in Rhizoma Chuanxiong through UPLC-MS-based multivariate statistical analysis

• Main Authors: Yi-Yao Yang (Author), Zhao-Yu Wu (Author), Fang-Bo Xia (Author), Hao Zhang (Author), Xu Wang (Author), Jian-Li Gao (Author), Feng-Qing Yang (Author), Jian-Bo Wan (Author)
• Format: Book
• Published: BMC, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The dry root and rhizome of Ligusticum chuanxiong Hort., or Chuanxiong, has been used as a blood-activating and stasis-removing traditional Chinese medicine for 1000 years. Our previous studies have shown the inhibitory activity on platelet and thrombin (THR) of Chuanxiong. THR a...