Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase

• Main Authors: Risheng Ye (Author), Qiong A. Wang (Author), Caroline Tao (Author), Lavanya Vishvanath (Author), Mengle Shao (Author), Jeffery G. McDonald (Author), Rana K. Gupta (Author), Philipp E. Scherer (Author)
• Format: Book
• Published: Elsevier, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The selective estrogen receptor modulator tamoxifen, in combination with the Cre-ERT2 fusion protein, has been one of the mainstream methods to induce genetic recombination and has found widespread application in lineage tracing studies. Methods & results: Here, we report that tamoxi...