A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor

• Asıl Yazarlar: Fa Zhang (Yazar), Emrah Altindis (Yazar), C. Ronald Kahn (Yazar), Richard D. DiMarchi (Yazar), Vasily Gelfanov (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective: Natural sources of molecular diversity remain of utmost importance as a reservoir of proteins and peptides with unique biological functions. We recently identified such a family of viral insulin-like peptides (VILPs). We sought to advance the chemical methods in synthesis to explore the s...