Pulmonary Targeting of Inhalable Moxifloxacin Microspheres for Effective Management of Tuberculosis

• Main Authors: Bhavya Vishwa (Author), Afrasim Moin (Author), D. V. Gowda (Author), Syed M. D. Rizvi (Author), Wael A. H. Hegazy (Author), Amr S. Abu Lila (Author), El-Sayed Khafagy (Author), Ahmed N. Allam (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the present study, the objective was to attain a localized lung delivery of an anti-tubercular fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non-invasive pulmonary route using inhalable microspheres as a dry powder inhaler approach. MXF-loaded poly (lactic-co-g...