A High-Throughput Phenotypic Screen of the 'Pandemic Response Box' Identifies a Quinoline Derivative with Significant Anthelmintic Activity

• Main Authors: Harrison T. Shanley (Author), Aya C. Taki (Author), Joseph J. Byrne (Author), Abdul Jabbar (Author), Tim N. C. Wells (Author), Kirandeep Samby (Author), Peter R. Boag (Author), Nghi Nguyen (Author), Brad E. Sleebs (Author), Robin B. Gasser (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parasitic nematodes cause diseases in livestock animals and major economic losses to the agricultural industry worldwide. Nematodes of the order Strongylida, including <i>Haemonchus contortus</i>, are particularly important. The excessive use of anthelmintic compounds to treat infections...