Oxidative and Inflammatory Imbalance in Placenta and Kidney of sFlt1-Induced Early-Onset Preeclampsia Rat Model

• Main Authors: Álvaro Santana-Garrido (Author), Claudia Reyes-Goya (Author), Pablo Espinosa-Martín (Author), Luis Sobrevia (Author), Luis M. Beltrán (Author), Carmen M. Vázquez (Author), Alfonso Mate (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Preeclampsia (PE) is a pregnancy-specific disorder characterized by the new onset of hypertension plus proteinuria and/or end-organ dysfunction. Here, we investigate the role of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system as a major component of reactive oxygen species gen...