The Synthetic Myeloperoxidase Inhibitor AZD3241 Ameliorates Dextran Sodium Sulfate Stimulated Experimental Colitis

• Main Authors: Gulfam Ahmad (Author), Belal Chami (Author), Yuyang Liu (Author), Angie L. Schroder (Author), Patrick T. San Gabriel (Author), Antony Gao (Author), Genevieve Fong (Author), XiaoSuo Wang (Author), Paul K. Witting (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic inflammatory bowel disease (IBD) is a condition with multifactorial pathophysiology. To date, there is no permanent cure and the disease is primarily managed by immunosuppressive drugs; long-term use promotes serious side effects including increased risk malignancies. The current study aimed...