Inhibition of WEE1 Suppresses the Tumor Growth in Laryngeal Squamous Cell Carcinoma

• Main Authors: Meng-Ling Yuan (Author), Pei Li (Author), Zi-Hao Xing (Author), Jin-Ming Di (Author), Hui Liu (Author), An-Kui Yang (Author), Xi-Jun Lin (Author), Qi-Wei Jiang (Author), Yang Yang (Author), Jia-Rong Huang (Author), Kun Wang (Author), Meng-Ning Wei (Author), Yao Li (Author), Jin Ye (Author), Zhi Shi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

WEE1 is a tyrosine kinase that regulates G2/M cell cycle checkpoint and frequently overexpressed in various tumors. However, the expression and clinical significance of WEE1 in human laryngeal squamous cell carcinoma (LSCC) are still unknown. In this study, we found that WEE1 was highly expressed in...