Dissolution Enhancement in Cocoa Extract, Combining Hydrophilic Polymers through Hot-Melt Extrusion

• Asıl Yazarlar: Ludmila A. G. Pinho (Yazar), Saulo G. Souza (Yazar), Ricardo N. Marreto (Yazar), Livia L. Sa-Barreto (Yazar), Tais Gratieri (Yazar), Guilherme M. Gelfuso (Yazar), Marcilio Cunha-Filho (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2018-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The aim of this study was to improve the physicochemical properties of cocoa extract (CE) using hot-melt extrusion (HME) for pharmaceutical proposes. A mixture design was applied using three distinct hydrophilic polymeric matrices (Soluplus, Plasdone S630, and Eudragit E). Systems obtained by HME we...