Identification of gene fusion transcripts by transcriptome sequencing in <it>BRCA1</it>-mutated breast cancers and cell lines

• Main Authors: Ha Kevin CH (Author), Lalonde Emilie (Author), Li Lili (Author), Cavallone Luca (Author), Natrajan Rachael (Author), Lambros Maryou B (Author), Mitsopoulos Costas (Author), Hakas Jarle (Author), Kozarewa Iwanka (Author), Fenwick Kerry (Author), Lord Chris J (Author), Ashworth Alan (Author), Vincent-Salomon Anne (Author), Basik Mark (Author), Reis-Filho Jorge S (Author), Majewski Jacek (Author), Foulkes William D (Author)
• Format: Book
• Published: BMC, 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Gene fusions arising from chromosomal translocations have been implicated in cancer. However, the role of gene fusions in <it>BRCA1</it>-related breast cancers is not well understood. Mutations in <it>BRCA1 </it&...