Influence of continuous renal replacement therapy on the plasma concentration of tigecycline in patients with septic shock: A prospective observational study

• Main Authors: Fang Huang (Author), Wen-Xiang Cao (Author), Yu-Ying Yan (Author), Tian-Tian Mao (Author), Xian-Wen Wang (Author), Dan Huang (Author), Yu-Shuang Qiu (Author), Wen-Jie Lu (Author), Dong-Jie Li (Author), Yu-Gang Zhuang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The influence of continuous renal replacement therapy (CRRT) on the steady-state plasma concentration of high-dose tigecycline was investigated in septic shock patients to provide references for drug dosing.Methods: In this prospective observational study, 17 septic shock patients present...