The Circadian Hormone Melatonin Inhibits Morphine-Induced Tolerance and Inflammation via the Activation of Antioxidative Enzymes

Opioids are commonly prescribed for clinical pain management; however, dose-escalation, tolerance, dependence, and addiction limit their usability for long-term chronic pain. The associated poor sleep pattern alters the circadian neurobiology, and further compromises the pain management. Here, we ai...

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Main Authors: Ing-Jung Chen (Author), Chih-Ping Yang (Author), Sheng-Hsiung Lin (Author), Chang-Mei Lai (Author), Chih-Shung Wong (Author)
Format: Book
Published: MDPI AG, 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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