Metallodrugs against Breast Cancer: Combining the Tamoxifen Vector with Platinum(II) and Palladium(II) Complexes
The luminal A-subtype of breast cancer, where the oestrogen receptor α (ERα) is overexpressed, is the most frequent one. The prodrug tamoxifen (<b>1</b>) is the clinically used agent, inhibiting the ERα activity via the formation of several active metabolites, such as 4-hydroxytamoxifen...
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Main Authors: | , , , , , , |
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Format: | Book |
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MDPI AG,
2023-02-01T00:00:00Z.
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A1234.567 |
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