MAR1 suppresses inflammatory response in LPS-induced RAW 264.7 macrophages and human primary peripheral blood mononuclear cells via the SIRT1/PGC-1α/PPAR-γ pathway

Abstract Background Sepsis is a complex syndrome characterized by a dysregulated inflammatory response to systemic infection and leads to shock, multiple organ failure and death especially if not recognized early and treated promptly. Previous studies have suggested Maresin 1 (MAR1) can alleviate sy...

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Main Authors: Wei Wang (Author), Rong-Li Xu (Author), Ping He (Author), Rui Chen (Author)
Format: Book
Published: BMC, 2021-02-01T00:00:00Z.
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3rd Floor Main Library

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