Fabrication, Optimization, and Evaluation of Rotigotine-Loaded Chitosan Nanoparticles for Nose-To-Brain Delivery

• Autors principals: Angeline Shak. Tzeyung (Autor), Shadab Md (Autor), Subrat Kumar Bhattamisra (Autor), Thiagarajan Madheswaran (Autor), Nabil A. Alhakamy (Autor), Hibah M. Aldawsari (Autor), Ammu K. Radhakrishnan (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2019-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The objective of the present study was to develop, optimize, and evaluate rotigotine-loaded chitosan nanoparticles (RNPs) for nose-to-brain delivery. Rotigotine-loaded chitosan nanoparticles were prepared by the ionic gelation method and optimized for various parameters such as the effect of chitosa...