Fabrication, Optimization, and Evaluation of Rotigotine-Loaded Chitosan Nanoparticles for Nose-To-Brain Delivery

• Main Authors: Angeline Shak. Tzeyung (Author), Shadab Md (Author), Subrat Kumar Bhattamisra (Author), Thiagarajan Madheswaran (Author), Nabil A. Alhakamy (Author), Hibah M. Aldawsari (Author), Ammu K. Radhakrishnan (Author)
• Format: Book
• Published: MDPI AG, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective of the present study was to develop, optimize, and evaluate rotigotine-loaded chitosan nanoparticles (RNPs) for nose-to-brain delivery. Rotigotine-loaded chitosan nanoparticles were prepared by the ionic gelation method and optimized for various parameters such as the effect of chitosa...