Ligands for oral delivery of peptides across the blood-brain-barrier

• Autori principali: Murad Al Gailani (Autore), Mengyang Liu (Autore), Jingyuan Wen (Autore)
• Natura: Libro
• Pubblicazione: Compuscript Ltd, 2022-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Peptides are short chains of amino acids linked by peptide bonds. Many peptides and proteins are limited by their poor enzymatic stability and permeability across the intestinal epithelial membranes and/or blood-brain barrier (BBB). Parenteral administration of these peptides is unfavorable because...