Exercise Regulates the Lactate Receptor HCAR1 and ERK1/2-PI3K/Akt Pathways to Promote Cerebral Angiogenesis

• Main Authors: Shicun Zhang (Author), Fang Wu (Author), Lan Zhan (Author), Wennan Lin (Author), Chunming Liang (Author), Yu Pang (Author), Jiawen Zhang (Author), Zhuang Mu (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: We aimed to explore the ole and mechanism of lactate receptor (HCAR1) in the angiogenesis of leptomeningeal fibroblast-like cells. Methods: Human brain fibroblast-like cells were selected and some cells were deactivated, analyzed and compared with HCAR1 mRNA and protein expressions in de...