Epigenetic Modifications to H3K9 in Renal Tubulointerstitial Cells after Unilateral Ureteric Obstruction and TGF-β1 Stimulation

• 主要な著者: Timothy D. Hewitson (著者), Stephen G. Holt (著者), Sven-Jean Tan (著者), Belinda Wigg (著者), Chrishan S. Samuel (著者), Edward R. Smith (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction: Epigenetic regulation of fibrogenesis through post-translational histone modifications (marks) may be a key determinant of progression in renal disease. In this study, we examined the distribution and acquisition of histone 3 Lysine 9 (H3K9) marks after injury and stimulation with the...