Effects of Erythromycin on Osteoclasts and Bone Resorption via DEL-1 Induction in Mice

• Main Authors: Hikaru Tamura (Author), Tomoki Maekawa (Author), Hisanori Domon (Author), Takumi Hiyoshi (Author), Satoru Hirayama (Author), Toshihito Isono (Author), Karin Sasagawa (Author), Daisuke Yonezawa (Author), Naoki Takahashi (Author), Masataka Oda (Author), Takeyasu Maeda (Author), Koichi Tabeta (Author), Yutaka Terao (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Macrolides are used to treat various infectious diseases, including periodontitis. Furthermore, macrolides are known to have immunomodulatory effects; however, the underlying mechanism of their action remains unclear. DEL-1 has emerged as an important factor in homeostatic immunity and osteoclastoge...