Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m<sup>6</sup>A Methylation of RNA in Acute Myeloid Leukemia Cells

N<sup>6</sup>A-methyladenosine (m<sup>6</sup>A) post-transcriptional modification, the most abundant internal RNA modification, is catalyzed by the METTL3-14 methyltransferase complex. Recently, attention has been drawn to the METTL3-14 complex regarding its significant roles...

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Main Authors: Je-Heon Lee (Author), Namjeong Choi (Author), Subin Kim (Author), Mi Sun Jin (Author), Haihong Shen (Author), Yong-Chul Kim (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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