Anti-metastatic Properties of Naproxen-HBTA in a Murine Model of Cutaneous Melanoma

• Main Authors: Giuseppe Ercolano (Author), Paola De Cicco (Author), Francesco Frecentese (Author), Irene Saccone (Author), Angela Corvino (Author), Flavia Giordano (Author), Elisa Magli (Author), Ferdinando Fiorino (Author), Beatrice Severino (Author), Vincenzo Calderone (Author), Valentina Citi (Author), Giuseppe Cirino (Author), Angela Ianaro (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The beneficial effects of H2S-release and of COXs-inhibition have been exploited in the design of novel anti-inflammatory drugs, the H2S-releasing non-steroidal anti-inflammatory drugs (H2S-NSAIDs), showing promising potential for chemoprevention in cancers. Here, we evaluated the efficacy of a new...