Diet-induced obesity impairs spermatogenesis: the critical role of NLRP3 in Sertoli cells

• Ngā kaituhi matua: Yang Mu (Author), Tai-lang Yin (Author), Yan Zhang (Author), Jing Yang (Author), Yan-ting Wu (Author)
• Hōputu: Pukapuka
• I whakaputaina: BMC, 2022-08-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Abstract Background Accumulating evidence indicates a key role of Sertoli cell (SC) malfunction in spermatogenesis impairment induced by obesity. Nucleotide-binding oligomerization domain-like receptor with a pyrin domain 3 (NLRP3) is expressed in SCs, but the role of NLRP3 in the pathological proce...