Characterization of Forskolin-Induced Ca2+ Signals in Rat Olfactory Receptor Neurons

• Main Authors: Ken-ichi Otsuguro (Author), Shree Hari Gautam (Author), Shigeo Ito (Author), Yoshiaki Habara (Author), Toshiyuki Saito (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Forskolin-induced Ca2+ signals were examined in isolated rat olfactory receptor neurons (ORNs) using a Ca2+ indicator, fura-2. In the soma of the ORNs, forskolin caused an increase in the intracellular Ca2+ concentration ([Ca2+]i) that was enhanced by a phosphodiesterase (PDE) 1 inhibitor, 8-methoxy...