Anti-Inflammatory Effects of RTD-1 in a Murine Model of Chronic <i>Pseudomonas aeruginosa</i> Lung Infection: Inhibition of NF-κB, Inflammasome Gene Expression, and Pro-IL-1β Biosynthesis
Vicious cycles of chronic airway obstruction, lung infections with <i>Pseudomonas aeruginosa</i>, and neutrophil-dominated inflammation contribute to morbidity and mortality in cystic fibrosis (CF) patients. Rhesus theta defensin-1 (RTD-1) is an antimicrobial macrocyclic peptide with imm...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
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MDPI AG,
2021-08-01T00:00:00Z.
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