Mangiferin ameliorates polycystic ovary syndrome in rats by modulating insulin resistance, gut microbiota, and ovarian cell apoptosis

• Main Authors: Zhang Yong (Author), Chen Mimi (Author), Li Yingjie (Author), Guo Yichen (Author), Yu Yansu (Author), Zhou Zhi (Author), Lu Hui (Author), Yao Si (Author), Wu Chongming (Author), Zhang Xiaopo (Author), Ma Ning (Author), Lu Weiying (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder characterized by hyperandrogenism, prolonged anovulation and polycystic ovaries. However, there are no effective interventions to treat this disorder. As previously shown, mangiferin modulated the AMPK and NLRP3 signal pa...