PGE2 Elevates IL-23 Production in Human Dendritic Cells via a cAMP Dependent Pathway

• Main Authors: Quanxing Shi (Author), Zhao Yin (Author), Bei Zhao (Author), Fei Sun (Author), Haisheng Yu (Author), Xiangyun Yin (Author), Liguo Zhang (Author), Shouli Wang (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PGE2 elevates IL-23 production in mouse dendritic cells while inhibits IL-23 production in isolated human monocytes. Whether this differential effect of PGE2 on IL-23 production is cell-type- or species-specific has not been investigated in detail. The present study was designed to investigate the e...