Acute Kidney Injury with SARS-CoV-2 Infection in Pediatric Patients Receiving High-Dose Methotrexate Chemotherapy: A Report of Three Cases

• Main Authors: Olga Nigro (Author), Cristina Meazza (Author), Elisabetta Schiavello (Author), Veronica Biassoni (Author), Nadia Puma (Author), Luca Bergamaschi (Author), Giovanna Gattuso (Author), Giovanna Sironi (Author), Virginia Livellara (Author), Gabriele Papagni (Author), Maura Massimino (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Methotrexate is renally excreted. HDMTX (high dose-methotrexate)-induced acute kidney injury (AKI) is a non-oliguric decrease in glomerular filtration rate (GFR) heralded by an acute rise in serum creatinine. Moreover, AKI is also a frequent complication of COVID-19. Among our patients t...